BETA
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RELA gene Interaction Network
RELA gene Pathways
| Symbol | RELA |
| Name | RELA proto-oncogene, NF-kB subunit |
| Type | transcription regulator |
| Synonyms | anon-EST:GressD7, CG6667, dl, Dmel CG6667, Dor, Dorsal, fs(2)k10816, GSd447, mat(2)dorsal, NF KAPPA B subunit P65, NF κ B subunit P65, NF-kappa B, NF-kappa B (p65), NF-κ B, NF-κ B (p65), NF-κB p65, NFkB, NFkB/p65, NFKB3, nos2, p65, p65 NFkappaB, p65 Nfkb, p65 NFκB, p65/Rela, RELA, RELA proto-oncogene, NF-kB subunit, v-rel avian reticuloendotheliosis viral oncogene homolog A, v-rel reticuloendotheliosis viral oncogene homolog A (avian), Xrel1, xrela |
| Species | Human (RELA EG:5970), Mouse (Rela EG:19697), Rat (Rela EG:309165), Cow (RELA EG:508233), Fruit Fly (dl EG:35047), Western Clawed Frog (rela EG:407869), Zebra Fish (rela EG:415099), Dog (RELA EG:483729) |
| SwissProt ID | Q04206, Q04207, P15330 |
| Summary | NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
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| Name | RELA gene summary |
| Description | Name: RELA proto-oncogene, NF-kB subunit, Symbol: RELA, Category: gene, Type: transcription regulator, Synonyms: anon-EST:GressD7, CG6667, dl, Dmel CG6667, Dor, Dorsal, fs(2)k10816, GSd447, mat(2)dorsal, NF KAPPA B subunit P65, NF κ B subunit P65, NF-kappa B, NF-kappa B (p65), NF-κ B, NF-κ B (p65), NF-κB p65, NFkB, NFkB/p65, NFKB3, nos2, p65, p65 NFkappaB, p65 Nfkb, p65 NFκB, p65/Rela, RELA, RELA proto-oncogene, NF-kB subunit, v-rel avian reticuloendotheliosis viral oncogene homolog A, v-rel reticuloendotheliosis viral oncogene homolog A (avian), Xrel1, xrela, Summary: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
