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Symbol MAPK3
Name mitogen-activated protein kinase 3
Type kinase
Synonyms DAC2, ERK-1, ERT2, Esrk1, fi06b09, FUS3, HS44KDAP, HUMKER1A, Mapk p44, MAPK1, MAPK3, Mapkapk3, mitogen-activated protein kinase 3, mitogen-activated serine/threonine-protein kinase FUS3, MNK1, MTAP2K, p44, p44 Erk, P44ERK1, P44MAPK, PRKM3, wu:fi06b09, YBL016W, zERK1
Species Human (MAPK3 EG:5595), Mouse (Mapk3 EG:26417), Rat (Mapk3 EG:50689), Baker's Yeast (FUS3 EG:852265), Cow (MAPK3 EG:531391), Zebra Fish (mapk3 EG:399480)
SwissProt ID P27361, Q63844, P21708, P16892
Summary The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
MAPK3 gene Interaction Network MAPK3 gene Pathways
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Name MAPK3 gene summary
Description Name: mitogen-activated protein kinase 3, Symbol: MAPK3, Category: gene, Type: kinase, Synonyms: DAC2, ERK-1, ERT2, Esrk1, fi06b09, FUS3, HS44KDAP, HUMKER1A, Mapk p44, MAPK1, MAPK3, Mapkapk3, mitogen-activated protein kinase 3, mitogen-activated serine/threonine-protein kinase FUS3, MNK1, MTAP2K, p44, p44 Erk, P44ERK1, P44MAPK, PRKM3, wu:fi06b09, YBL016W, zERK1, Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008]
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