BETA
Loading nodecard... 
PRKCZ gene Interaction Network
PRKCZ gene Pathways
| Symbol | PRKCZ |
| Name | protein kinase C zeta |
| Type | kinase |
| Synonyms | 14-3-3-zetaisoform, AI098070, aPKCzeta, aPKCζ, C80388, NPKC-ZETA, NPKC-ζ, PKC-ZETA, PKC-ζ, PKC2, Pkcz, PKMz, Prkc zeta, Prkc ζ, PRKCZ, protein kinase C zeta, protein kinase C ζ, protein kinase C, zeta, protein kinase C, ζ, r14-3-3, R74924, si:ch211-150o23.4, TPKC, zetaPKC |
| Species | Human (PRKCZ EG:5590), Mouse (Prkcz EG:18762), Rat (Prkcz EG:25522), Cow (PRKCZ EG:286877), Western Clawed Frog (prkcz EG:100101769), Zebra Fish (prkcz EG:555737), Dog (PRKCZ EG:479577) |
| SwissProt ID | Q05513, Q02956, P09217 |
| Summary | Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Heres a message for genes.
Loading node summary...
Heres a message for genes.
Flash version 10.2+ is required to view Pathways.
| Name | PRKCZ gene summary |
| Description | Name: protein kinase C zeta, Symbol: PRKCZ, Category: gene, Type: kinase, Synonyms: 14-3-3-zetaisoform, AI098070, aPKCzeta, aPKCζ, C80388, NPKC-ZETA, NPKC-ζ, PKC-ZETA, PKC-ζ, PKC2, Pkcz, PKMz, Prkc zeta, Prkc ζ, PRKCZ, protein kinase C zeta, protein kinase C ζ, protein kinase C, zeta, protein kinase C, ζ, r14-3-3, R74924, si:ch211-150o23.4, TPKC, zetaPKC, Summary: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
