BETA
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PRKCE gene Interaction Network
PRKCE gene Pathways
| Symbol | PRKCE |
| Name | protein kinase C epsilon |
| Type | kinase |
| Synonyms | 5830406C15RIK, 98F, CG1954, CLY15, CLY5, CLY7, Dmel CG1954, Dpkc3, dPKC98F, fj59b07, HPO2, Nc98F, nPKC, nPKC-epsilon, nPKC-ε, PK-C, PKC d98F, PKC ε, PKC-98F, PKC1, Pkc3, PKC98C, Pkc98E, PKC[e], PKCE, PKCepsilon, PRKCE, prkcea, prkceb, Protein C kinase 98E, protein kinase C, protein kinase C epsilon, protein kinase C ε, protein kinase C, epsilon, protein kinase C, epsilon a, protein kinase C, epsilon b, protein kinase C, ε, protein kinase C, ε a, protein kinase C, ε b, R75156, si:ch211-243f3.2, STT1, wu:fj59b07, YBL105C |
| Species | Human (PRKCE EG:5581), Mouse (Prkce EG:18754), Rat (Prkce EG:29340), Baker's Yeast (PKC1 EG:852169), Cow (PRKCE EG:507041), Fruit Fly (Pkc98E EG:43428), Western Clawed Frog (prkce EG:100135720), Zebra Fish (prkcea EG:100005075), Zebra Fish (prkceb EG:100332055) |
| SwissProt ID | Q02156, P16054, P09216, P24583, P13678 |
| Summary | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008] |
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| Name | PRKCE gene summary |
| Description | Name: protein kinase C epsilon, Symbol: PRKCE, Category: gene, Type: kinase, Synonyms: 5830406C15RIK, 98F, CG1954, CLY15, CLY5, CLY7, Dmel CG1954, Dpkc3, dPKC98F, fj59b07, HPO2, Nc98F, nPKC, nPKC-epsilon, nPKC-ε, PK-C, PKC d98F, PKC ε, PKC-98F, PKC1, Pkc3, PKC98C, Pkc98E, PKC[e], PKCE, PKCepsilon, PRKCE, prkcea, prkceb, Protein C kinase 98E, protein kinase C, protein kinase C epsilon, protein kinase C ε, protein kinase C, epsilon, protein kinase C, epsilon a, protein kinase C, epsilon b, protein kinase C, ε, protein kinase C, ε a, protein kinase C, ε b, R75156, si:ch211-243f3.2, STT1, wu:fj59b07, YBL105C, Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008] |
