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Symbol PRKCA
Name protein kinase C alpha
Type kinase
Synonyms AAG6, AI875142, CG6622, Dmel CG6622, DPKC, Dpkc1, dPKC53E(br), im:7139045, LOC146784, PK-C, PKC-53B, PKC-alpha, PKC-α, PKC1, Pkc53E, PKCA, PKRCA, PRKACA, PRKCA, Protein C kinase 53E, protein kinase C alpha, protein kinase C α, protein kinase C, alpha, protein kinase C, α, si:dkey-8l19.1, XPKCI, α-protein kinase C
Species Human (PRKCA EG:5578), Mouse (Prkca EG:18750), Rat (Prkca EG:24680), Cow (PRKCA EG:282001), Fruit Fly (Pkc53E EG:48311), Western Clawed Frog (prkca EG:780209), Zebra Fish (prkca EG:497384), Dog (PRKCA EG:490904)
SwissProt ID P17252, P20444, P05696, P04409, P05130
Summary Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
PRKCA gene Interaction Network PRKCA gene Pathways
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Name PRKCA gene pathways
Description Name: protein kinase C alpha, Symbol: PRKCA, Category: gene, Type: kinase, Synonyms: AAG6, AI875142, CG6622, Dmel CG6622, DPKC, Dpkc1, dPKC53E(br), im:7139045, LOC146784, PK-C, PKC-53B, PKC-alpha, PKC-α, PKC1, Pkc53E, PKCA, PKRCA, PRKACA, PRKCA, Protein C kinase 53E, protein kinase C alpha, protein kinase C α, protein kinase C, alpha, protein kinase C, α, si:dkey-8l19.1, XPKCI, α-protein kinase C, Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes. [provided by RefSeq, Jul 2008]
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