BETA
Loading nodecard... 
GRB2 gene Interaction Network
GRB2 gene Pathways
| Symbol | GRB2 |
| Name | growth factor receptor bound protein 2 |
| Type | kinase |
| Synonyms | 24/1, AA408164, ASH, Ash-psi, CG6033, crkl, Dmel CG6033, downstream of receptor kinase, drk, Drk/Grb2, E(sev)2B, EGFRBP-GRB2, fb18e12, GRAB2, Grb/drk, GRB2, grb2-a, grb2-b, Grb2/drk, Grb3-3, growth factor receptor bound protein 2, growth factor receptor-bound protein 2b, l(2)10626, l(2)k13809, MST084, MSTP084, NCKAP2, P1112, Su(sev)R1, wu:fb18e12, wu:fb34e06, zgc:73077 |
| Species | Human (GRB2 EG:2885), Mouse (Grb2 EG:14784), Rat (Grb2 EG:81504), Cow (GRB2 EG:535298), Fruit Fly (drk EG:36497), Western Clawed Frog (grb2 EG:493492), Zebra Fish (grb2b EG:406308) |
| SwissProt ID | P62993, Q60631, P62994, Q08012, Q66II3 |
| Summary | The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Heres a message for genes.
Loading node summary...
Heres a message for genes.
Flash version 10.2+ is required to view Pathways.
| Name | GRB2 gene summary |
| Description | Name: growth factor receptor bound protein 2, Symbol: GRB2, Category: gene, Type: kinase, Synonyms: 24/1, AA408164, ASH, Ash-psi, CG6033, crkl, Dmel CG6033, downstream of receptor kinase, drk, Drk/Grb2, E(sev)2B, EGFRBP-GRB2, fb18e12, GRAB2, Grb/drk, GRB2, grb2-a, grb2-b, Grb2/drk, Grb3-3, growth factor receptor bound protein 2, growth factor receptor-bound protein 2b, l(2)10626, l(2)k13809, MST084, MSTP084, NCKAP2, P1112, Su(sev)R1, wu:fb18e12, wu:fb34e06, zgc:73077, Summary: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
