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Symbol SPART
Name spartin
Type other
Synonyms AI840044, C79168, KIAA0610, mKIAA0610, SPART, sparta, SPARTIN, spartin a, SPG20, spg20a, TAHCCP1, zgc:172059
Species Human (SPART EG:23111), Rat (Spart EG:295053), Western Clawed Frog (spart EG:100170472), Zebra Fish (sparta EG:100005765)
SwissProt ID Q8N0X7
Summary This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]
SPART gene Interaction Network SPART gene Pathways
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Name SPART gene interaction network
Description Name: spartin, Symbol: SPART, Category: gene, Type: other, Synonyms: AI840044, C79168, KIAA0610, mKIAA0610, SPART, sparta, SPARTIN, spartin a, SPG20, spg20a, TAHCCP1, zgc:172059, Summary: This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]
Heres a message for genes.
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