BETA
Loading nodecard... 
EGFR gene Interaction Network
EGFR gene Pathways
| Symbol | EGFR |
| Name | epidermal growth factor receptor |
| Type | kinase |
| Synonyms | 9030024J15RIK, AI552599, C-ERBB, EGF receptor, EGF-TK, EGFR, EGFR vIII, EGFR1, EGFR12, EGFR15, egfra, epidermal growth factor receptor, epidermal growth factor receptor a (erythroblastic leukaemia viral (v-erb-b) oncogene homolog, avian), epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), ERBB, ERBB1, Errb1, Errp, HER-1 (EGFR), HER1, MENA, NISBD2, PIG61, wa-2, Wa5, XEgfr |
| Species | Human (EGFR EG:1956), Mouse (Egfr EG:13649), Rat (Egfr EG:24329), Cow (EGFR EG:407217), Western Clawed Frog (egfr EG:100492965), Zebra Fish (egfra EG:378478), Dog (EGFR EG:404306) |
| SwissProt ID | P00533, Q01279 |
| Summary | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016] |
Heres a message for genes.
Loading node summary...
Heres a message for genes.
Flash version 10.2+ is required to view Pathways.
| Name | EGFR gene summary |
| Description | Name: epidermal growth factor receptor, Symbol: EGFR, Category: gene, Type: kinase, Synonyms: 9030024J15RIK, AI552599, C-ERBB, EGF receptor, EGF-TK, EGFR, EGFR vIII, EGFR1, EGFR12, EGFR15, egfra, epidermal growth factor receptor, epidermal growth factor receptor a (erythroblastic leukaemia viral (v-erb-b) oncogene homolog, avian), epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), ERBB, ERBB1, Errb1, Errp, HER-1 (EGFR), HER1, MENA, NISBD2, PIG61, wa-2, Wa5, XEgfr, Summary: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016] |
